Prof. de Weck's research is in Systems Science and Engineering. He focuses on how complex man-made systems such as aircraft, spacecraft, cyber-physical products, and critical infrastructures are designed, manufactured and operated and how they evolve over time.  His main emphasis is on the strategic properties of these systems that have the potential to maximize lifecycle value. His group has developed quantitative methods and tools that explicitly consider manufacturability, flexibility, robustness, and sustainability among other characteristics. Significant results include the Adaptive Weighted Sum (AWS) method for resolving tradeoffs amongst competing objectives, the Delta-Design Structure Matrix (DDSM) for technology infusion analysis, Time-Expanded Decision Networks (TDN) and the SpaceNet and HabNet simulation environments. These methods have impacted complex systems in space exploration (NASA, JPL), oil and gas exploration (BP) as well as sophisticated electro-mechanical products (e.g. Xerox, Pratt & Whitney, GM, DARPA). He has authored or co-authored three books, 250 peer-reviewed articles and won 8 best paper and best poster awards since 2004. He is a Fellow of INCOSE and an Associate Fellow of AIAA. From 2008 to 2011 he served as Associate Director of the Engineering Systems Division (ESD) at MIT. From 2010 to 2013 he served as Executive Director of the MIT Production in the Innovation Economy (PIE) project. Since January 2013 he serves as Editor-in-Chief of the journal Systems Engineering.